Making the Decision. The decision to move on from In Vitro Fertilization (IVF) to a donor egg IVF cycle is a very personal one. You may see your funds running out, with no clear understanding of why IVF is not working for you. Some women in this situation may have gone through three cycles of IVF or more without success. Others may be experiencing recurrent miscarriages with no clear explanation as to the reason. So, at some point in your infertility treatment, you may find yourself at crossroads.